COVID- 19 Testing for Travel

Fast, Accurate COVID-19 Testing for Travel

More countries, states, and companies are requiring a negative COVID-19 test prior to travel or entry.  With rapid and accurate testing, TargetDx Laboratory can provide expedited same day test results*.

TargetDx Laboratory is a CLIA certified lab and we offer both COVID-19 PCR and Antigen Viral Test and COVID-19 Antibody Test. These tests are only authorized for Emergency Use Authorization (EUA) and performed by laboratories in the United States who are certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA), 42 U.S.C. §263a, to perform high complexity tests.

TargetDx Laboratory’s COVID-19 test results are accepted for most travel interstate and internationally.

TargetDx Laboratory is an approved testing institution by the Chinese Consulate General in San Francisco for both COVID-19 Nucleic Acid, Serology IgM Antibody, and Antigen tests for travel to China. We offer expedited test services for traveling to China. Learn more about our Covid testing for travel to China.

COVID-19 PCR Viral Test (COVID-19 Nucleic Acid Test)

COVID-19 PCR Viral Test is a molecular test for active infection, and it involves collecting swab specimens from your nose or throat.

The COVID-19 PCR Viral Test is a nucleic acid amplification test (NAAT) utilizing real-time reverse transcription-polymerase chain reaction (RT-PCR) intended for the qualitative detection of nucleic acid from SARS-CoV-2.

We expect the new variant from the UK, B.1.1.7, and others, to be detected by our test because it screens for three regions of interest:

  • S Gene (Spike protein)
  • N Gene (Nuclear Capsid protein; at virus’ core)
  • ORF Gene

The UK B.1.1.7 variant has most of its mutations in the S protein, so even if the RT-PCR does not detect the variant’s S gene, it still detects both N & ORF genes.

The COVID-19 PCR Viral Test currently performed by TargetDx Laboratory has been validated for FDA EUA for the current pandemic. Based on a validation study using 20 bronchoalveolar lavage (BAL) and 20 nasopharyngeal (NP) swabs, the test was able to detect 100% of positive specimens accurately.

The typical turnaround time is 6 – 12 hours** for travel testing. Typically, the quickest way to get your test results is to have them sent to you through a secure online portal or to your email in an encrypted and password-protected format.

* Appointment times for travel testing are 8:00 AM to 4:30 PM on Tuesday – Saturday and 8:00 AM to 1:00 PM on Sunday.

Test results from specimens collected on Sunday are not released until Tuesday afternoon.

An appointment is required, but we will try to accommodate walk-ins as necessary.

**If a test comes back inconclusive, it will be retested and may incur a longer turnaround time (usually completed within the same day of sample receipt from the lab).

COVID-19 Viral Tests we offer are:

  • COVID-19 NAAT RT-PCR
  • COVID-19, FluA/B, RSV NAAT RT-PCR
  • COVID-19 Rapid PCR Test
  • COVID-19, FluA/B Rapid PCR Test
  • COVID-19 Antigen Test

COVID-19 Antibody Test

The COVID-19 antibody test has been approved to identify recent or prior infection to SARS-CoV-2 and it is not intended to diagnose a current infection or to rule out an active COVID-19 infection. It involves a simple blood draw.

For the antibody test (post-infection), TargetDx Laboratory utilizes an enzyme-linked immunoassay (ELISA) (IgM, IgG, and IgA combined) and a colloidal gold assay (IgM or IgG independent) for the in-vitro qualitative detection of antibodies to SARS-CoV-2 in human serum and plasma. The test is intended to aid in the determination of the immune reaction to SARS-CoV-2.

The antibody tests currently offered by TargetDx Laboratory have specificity values of 99.5% which keeps false-positive results to a minimum. The antibody test sensitivity values are approximately 99.5% to 100%.

Our antibody tests have met validation standards and have been granted Emergency Use Authorizations (EUA) by the FDA for public health and clinical use.

Turnaround time for the COVID-19 Antibody Test is typically 8-24 hours from the time the specimen is received in our laboratory. We offer expedited services for patients traveling.

COVID-19 Antibody Tests we offer are:

  • COVID-19 N Antibody Test (IgM or IgG), Lateral Flow Assay (e.g., Colloidal Gold)
  • COVID-19 S Antibody Test (IgM or IgG), Lateral Flow Assay (e.g., Colloidal Gold)
  • COVID-19 N Antibody Test (IgM, IgG, and/or IgA), Immunoassay
  • COVID-19 S Antibody Test (IgM, IgG, and/or IgA), Immunoassay

Site Testing

TargetDx Laboratory also provides normal (non-travel) testing to the public. We work with schools, government agencies, private sectors, and more. If you would like to set-up testing for your organization, please email us.

FAQ for Travel

What are the requirements for testing for travel?

Each country, state, and airline have their own requirements for travel. TargetDx COVID-19 PCR Viral Test results are accepted for most travel interstate and internationally. TargetDx Laboratory is currently not doing testing for Hawaii travelers. Hawaii travelers must get tested with preferred lab vendors by the state of Hawaii.

Get tested with a PCR viral test 1-3 days before you travel. Keep a copy of your test results with you during travel in case you are asked for them. Do NOT travel if you test positive.

Please check travel testing requirements by the country or state to which you are traveling. Below are some resources for travel information:

There are more sites for information. Please do your due diligence and check the testing requirements before traveling to a state, country, or through an airline.

How can I book an appointment and what are your hours?

An appointment can be booked online at www.targetdxlab.com. Click Book Your Test and follow the instructions.

Our business hours are from 9 AM to 5 PM, Monday to Friday.

Appointment times for travel testing are 8 AM to 4:30 PM on Tuesday to Saturday, and 8 AM to 1 PM on  Sunday.

Test results from specimens collected on Sunday are not released until Tuesday afternoon.

An appointment is required, but we will try to accommodate walk-ins as necessary.

What does the COVID-19 Testing for Travel to China Package include?

RT-PCR tests used for international travel are released within the same day between 4-6 PM. China Travel Package includes PCR, Antigen, and/or Antibody tests, documentation, and submission to the consulate at the appropriate turnaround times. Learn more about testing to travel to China.

Are both nucleic acid and serology IgM antibody COVID19 tests available at TargetDx Laboratory?
  • Both nucleic acid and Serology (IgG, IgM, and IgA combined, and individual testing for IgM and IgG) antibody tests are available at TargetDx. The following tests are available:
    • COVID-19 NAAT RT-PCR Viral Test (detect ORF1ab, N, and S genes of SARS-CoV-2)
    • COVID-19 Rapid PCR Viral Test (detect E and N genes of SARS-CoV-2)
    • COVID-19 Antibody Test Enzyme-Linked Immunosorbent Assay (detects IgM, IgG, and IgA combined)
    • COVID-19 Antibody Test Colloidal Gold (detects IgM or IgG independently)
Can the travel test reports be produced within 5-12 hours after the collection of the specimen?

Yes, the travel reports are produced within 5 – 12 hours.

Does TargetDx Laboratory have the testing licenses from the US relevant health departments?

Yes, we are in full compliance with the federal and CA state CLIA regulations and use only FDA EUA approved tests. We can provide FDA letters, a performance summary of our platforms, and copies of our CLIA licenses.

Is the specimen type (i.e., serum, plasma, venous serum) on the test report?

Yes, the report explicitly states the specimen type used for the test. For example, we use serum/venous serum or plasma for the antibody test or nasopharyngeal for the RT-PCR test.

Will the test report indicate the specific testing method (i.e., colloidal gold, Immunoassay)?

We use two methods for the Antibody test which are 1) Immunoassay: enzyme-linked immunosorbent assays (ELISA) for combined IgM, IgG, and IgA and 2) Colloidal Gold/Lateral Flow (IgM only, IgG only). We do have both the anti-S and the anti-N.

The method for the Nucleic Acid Amplification Test (NAAT) is Reverse Transcriptase Polymerase Chain Reaction (RT-PCR).

These are indicated in the report.

Does TargetDx have its own CLIA-certified lab? If so, where?

TargetDx Laboratory is a fully certified CLIA Laboratory by the Laboratory Field Services (LFS) and the State of California for High Complexity Testing: State ID: CLF-90001713, CLIA ID: 05D2194953. All methods and platforms employed by TargetDx Laboratory are FDA EU approved.

We are located at 6541 Via Del Oro, Suite A, San Jose, CA 95119. Our phone is 219-510-0120. Emails regarding the test can be sent to info@targetdxlab.com.

Do you have another location where I can get my samples collected?

Please email us for information. TBA.

How do I get my test result?

Testees will register for an account online on our patient portal. When test results are released between 7-10 pm the same day, the Testee will be sent an email with an encrypted and password-protected PDF copy of their result, and instructions on how to access their report on their portal. Results are also submitted to the SF Chinese Consulate-General e-mailbox for China travelers.

Why are the COVID-19 test results for travel to China sent to the SF Chinese Consulate-General e-mailbox?

Results for COVID-19 testing for travel to China are sent to the SF Chinese Consulate-General e-mailbox at the request of the Consulate-General. This allows them to confirm the authenticity of the report submitted by the patient.

What are the testing requirements for Traveling to China?

The consulate’s policy regarding testing to travel to China:

http://www.chinaconsulatesf.org/zytz/202201/t20220105_10479063.htm

http://www.chinaconsulatesf.org/eng/zytz/202110/t20211009_9536873.htm

 

As of April 22, 2022, the new testing requirements set forth by the Chinese Consulate General are:

  • Travelers are required to do a PCR test 7 days before the flight date.
  • Then, based on the Traveler’s vaccination status, one will need to do other tests (i.e., two PCR tests or a PCR and two antibody test) 1 day before the flight date.
  • Travelers are required to have 2 PCR tests using 2 different platforms if one has been vaccinated with inactivated viral origin (i.e., CoronaVax, Sinopharm, Sinovac, Vero)
  • Travelers are required to have an anti-S and an anti-N antibody test if one has been vaccinated with mRNA/non-viral origin (i.e., Pfizer, Moderna, or J&J, Astra Zeneca, Anhui Zhifei, CanSino, Convidecia, RBD dimer.) or non-Vaccinated travelers.
  • Travelers now need to do an Antigen test the day before the flight. Antigen test report is NOT required when applying the health code. Airlines will inspect the original reports before check-in or boarding. Either printed or electronic original report will be accepted, while the result must be “negative”.
Can I order this test online for myself?

Yes, you can order the test online by clicking on Book Your Test.

Is COVID-19 testing for travel covered by my insurance?

Insurance does not typically cover travel testing. However, some insurance might. You should call your insurance and find out. You will first need to pay out of pocket and submit for reimbursement per your insurance company’s instructions.

How does the vaccine affect my antibody test result?

We have two antibody tests, the S protein antibody test and the N protein antibody test. If you have been vaccinated by Moderna, Pfizer, or Janssen, your S antibody will most likely be positive. If you have previously been infected with the COVID19 virus, then your N antibody would be positive. If you have been vaccinated by the mRNA vaccines, and never been infected, you may have a positive S antibody and a negative N antibody.

We have both the Immunoassay and lateral flow assay (aka colloidal gold) platforms to test for N and S protein. Our N Protein immunoassay has a specificity of 99.8% and a sensitivity of 99.5%. Our S Protein immunoassay has a specificity of 100% and sensitivity of 96.6%. More than 6,000-10,500 samples were tested for validation for the immunoassay.  Our S Protein lateral flow test has a sensitivity and specificity of 100% for IgM and 97.5% for IgG. More than 80 samples were tested for validation for the lateral flow test. Both tests are FDA EUA approved.

To account for vaccinated individuals, antibody testing requirements have been updated by the Chinese Consulate-General. Travelers to China are required to have an anti-S antibody test, and an anti-N protein antibody test if positive on the S Protein. If you have been vaccinated, you may be and are likely to be positive for the S Protein. You will then be tested for the N protein. If you are S Protein Positive, N Protein Negative, RT-PCR Negative, and Vaccinated with Moderna, Pfizer, or Janssen, you should be fine to travel to China. Should you test positive on the S Protein, we will process your sample on the N protein as required by the Chinese Consulate General at no extra cost.

What if I have not received my results?

Results are normally sent out by email and through the patient portal within the same day between 7-10 pm. If you have not received them by 9 pm, check your portal and in your spam and junk folders in your email. When checking your junk folder, you may need to do a search for “targetdxlab”.

How do the mutations affect our NAAT RT-PCR COVID-19 Test?

Our molecular test detects multiple (ORF1, S, and N) SARS-CoV-2 Targets and an MS2 phage and has a sensitivity and specificity of >99.9. Since this test is designed to detect multiple genetic targets, the overall test sensitivity should not be impacted by current variant mutations. Our RT-PCR test covers all variants.